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“Our objective is to understand feminine reproductive ageing, and why fertility quickly declines commencing from the mid-30s,” says Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata performs.
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Using the GCRLE grant, Munakata and Namekawa will search extra carefully at how oocytes are genomically primed and stored for later use. They will investigate the function of a chromatin remodeler in oocyte survival and fertility.
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Get the job done by Namekawa and Munakata suggests that a vital function occurs round the time of beginning: the nascent egg cells enter a holding sample, with their DNA precisely packaged and primed for fertilization later on in life.
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Yasuhisa Munakata, a postdoctoral fellow in the College of Biological Sciences, has acquired a grant to review how egg cells during the ovary alter after a while.
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